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KMID : 0363320170380020284
Journal of Korean Oriental Internal Medicine
2017 Volume.38 No. 2 p.284 ~ p.288
A Case Report of the Use of Traditional Korean Medicine to Treat a Patient with Chronic Hepatitis B Whose HBV-DNA Level Failed to Drop Below Undetectable Levels Following Long-term Treatment with Entecavir
Han Chang-Woo

Abstract
The patient presented to the clinic with the complaint of severe fatigue. The patient had been diagnosed with chronic hepatitis B a number of years earlier. Although he had used entecavir, an antiviral agent, for over two years, his HBV-DNA level had not dropped below undetectable levels. The fatigue seemed to be associated with chronic hepatitis B. Traditional Korean medicine (TKM) therapy for chronic hepatitis B was administered in conjunction with entecavir and at the same dose. The excessive fatigue gradually decreased following the treatment. On the 28th day, laboratory tests revealed that the patient¡¯s bilirubin level was slightly lower and that his HBV-DNA level had dropped below undetectable levels. The addition of TKM therapy may have contributed to the HBV-DNA clearance. No similar cases have been reported in Korea. Herein, we summarize the patient¡¯s progress.
KEYWORD
chronic hepatitis B, traditional Korean medicine, entecavir, HBV-DNA
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